Endocrine Abstracts

Background: Pregnancy is a state of insulin resistance that can predict diabetes development in some women, and is associated with increased risk for neonate and for mother. Frequency of glucose intolerance may be increased in the follow-up years.Aim: The aim of this study is to determine the presence of risk factors for type 2 diabetes and degree of glucose tolerance in population of pregnant women.Materials and methods: The study...

Background: The levels of maternal thyroid hormone concentrations increase from early pregnancy, with a mild increase in free hormones in the first trimester with a corresponding lowering of serum TSH. Thyroid autoantibodies are found in 5–15% of women during childbearing age, and chronic autoimmune thyroiditis is the main cause of hypothyroidism. Thyroid hormone contributes critically to normal fetal brain development. In the first trimester, the ‘normal’ range...

Introduction: The prevalence of hyperlipidemia in type 1 diabetics is 30 to 90%. High total cholesterol, LDL and triglyceride serum level is independent risk factor for cardiovascular disease. High prevalence of malignant atherogenic profile is alarming in type 1 diabetics (high triglyceride, low HDL). It is very often that dislipidemia is associated with diabetes and obesity, as well as hypertension, that pointed to inherited disorders.The aim of this s...

Introduction: Some physiological changes in HbA1c during pregnancy should be considered to determine its optimal value for glycemic control. Erythrocytes half-life decreases during pregnancy, which is reflected in a decrease in HbA1c.Aim: The aim of this study is to analyse HbA1c during pregnancy in healthy population of pregnant woman. Matherial and methods: The study included 77 pregnant women in the first trimester registered in Center for endocrinolo...

Introduction: The basic characteristics of metabolism in pregnancy are changes from anabolic to catabolic conditions with an increase in insulin resistance, moderate, reversible increase in lipid concentration in the blood, and accumulation of fat stores in the mother’s tissues. Lipid metabolism is essential for the development of healthy pregnancy, and fatty acids are a significant source of energy and a key element for membrane synthesis, while cholesterol, in addition ...

Background: Pregnancy presents a state of insulin resistance that can predipose diabetes development in some women, and is associated with increased risk for neonate and for mother. Gestational diabetes is a period of glucose intolerance that manifests at the beginning of the third trimester.Aim: The aim of this study is to analyse glycoregulation in healthy pregnant women.Materials and methods: This study included 77 healthy pregn...

Introduction: The basic characteristics of metabolism in pregnancy are changes from anabolic to catabolic conditions. During early gestation, the fetus is dependent on maternal thyroid hormones that cross the placenta. Thyroid disease in pregnancy is a common clinical problem, at least 2–3% of women have thyroid dysfunction. Pre-conceptual education and appropriate diagnosis and treatment of thyroid dysfunction in early pregnancy are of great importance, with the aim of ...

Introduction: High total cholesterol (tChol), LDL and trygliceride (TAG) level is independent risk factor for cardiovascular disease. High prevalence of malignant atherogenic profile is alarming in type 2 diabetics (high triglyceride, low HDL). It is very often that dislipidemia is associated with diabetes and obesity, as well as hypertension.Aim: The aim of this study is to analyse lipid profile in patients with type 2 diabetes in Kragujevac depending o...

Hyperlipidemia is common among patients with ST-elevation myocardial infarction (STEMI) and is associated with high risk of mortality and morbidity. Hypertriglyceridemia and low HDL cholstereol are independent risk factor for cardiovascular disease.Aim: The aim of this study is to analyse lipid profile in patients with STEMI with and without diabetes.Material and methods: This study included all patients registered in Coronary Unit...

High admission plasma glucose (APG) levels after ST-segment elevation acute myocardial infarction (STEMI) are common and associated with an increased risk of death in subjects with and without known diabetes.Aim: The aim of this study is to analyse the short and long term prognostic significance of APG in patients with STEMI with and without diabetes.Material and methods: This study included all patients registered in Coronary Unit...